Idan kun taɓa fuskantar matsalar rashin jin magana a cikin danginku, tabbas likita ko kwararre, tun ma kafin fara aikinsu, zasu yi muku gargaɗi cewa daidai kunne yana daya daga cikin hadaddun tsarin da dan adam zai fuskantaIrin wannan shine yanayin lokacin da ya karye, ya kasa ko ya lalace, kusan ba zai yuwu a gyara ba.
Da wannan a zuciyata, a yau ina son fada muku game da wani sabon ci gaba da ƙungiyar masu bincike suka samu wanda ya ƙunshi masana kimiyya daga China da Amurka, godiya ga fasaha. CRISPR, warkar da rashin jin haihuwa na haihuwa, don wannan dalili, na allura guda.
Godiya ga amfani da CRISPR, ƙungiyar masu bincike na iya samo magani don rashin jin haihuwa
Idan muka shiga wani karin bayani dalla-dalla kuma musamman la'akari da abin da aka buga a cikin takarda sakamakon wannan binciken, da alama masana kimiyya sun yi aiki don gano bambanci tsakanin kwayar halittar da ke dauke da wannan nau'ikan cutar ta rashin ji tare da wanda aka samo daga mai lafiya mutum. Sakamakon ya kasance wurin da karamin maye gurbi na kwayar TMC1 wanda ke haifar da wannan kwayar halitta don samar da furotin wanda ke lalata cilia.
A bayyane yake daidai wannan lalacewar cilia ne, ke da alhakin sauya sauti zuwa motsin jijiyoyi, wanda a ƙarshe ya haifar da abin da aka sani da kurumtar haihuwa. Don bamu ra'ayi, kawai ku gaya muku cewa maye gurbi karami ne, don haka kwafin kwayar halitta mai lafiya ya bambanta da kirtani tare da maye gurbi da harafi ɗaya kawai. Da zarar matsalar ta samo asali, ta hanyar aikin da ya wuce kima, dole ne a nemo mata magani.
Takesaya ne kawai daga cikin iyayen yake da wannan matsalar don childa toansu su gaji ta
Don haka mun dan fahimci matsalar rashin jin dadin haihuwa, kawai ku gaya muku, a cewar masana kimiyya, da alama kawai ya zama dole daya daga cikin iyayen ya same shi. Wannan isa ka ba yaranka. Kamar yadda tabbas zakuyi tunani, kodayake kamar dai akasin haka ne, gaskiyar magana shine muna fuskantar maye gurbi wanda yafi kowa a cikin al'umma fiye da yadda zamu iya gaskatawa.
Kamar yadda yayi tsokaci a maganganun Fyodor Urnov ne adam wata, daya daga cikin marubutan wannan aikin kuma farfesa a Altius Institute for Biomedical Sciences a Seattle:
Kamar dai mawaƙa biyu suna yin waƙa. Idan ɗayanku ya yi kuskure, dole ne a ɗora shi baki ɗaya don jin daidai waƙar. Ba za mu iya dakatar da mawaƙa biyu a lokaci guda ba, saboda wannan waƙar za ta daina.
Ta wannan, abin da Fyodor Urnov yake nufi shi ne cewa a cikin neman magani, ba wai kawai dole ne ya kashe kwayar halittar da ta sami maye gurbi ba, amma kuma dole ne ya san ainihin abin da yake.
Sakamakon wannan aikin ya farantawa dukkanin masana kimiyya rai
Don neman magani, masana kimiyya waɗanda sukayi aiki akan aikin sun yi amfani da ƙaramin tsarin RNA don gano kwayar halittar da ya kamata a kashe. Godiya ga wannan, sakamakon aikin, maye gurbi wanda ya haifar furotin din da ya haifar da kurumtar haihuwa an kashe shi.
A halin yanzu dole ne a tuna cewa wannan aikin yana cikin farkon farkon ci gaban sa, kodayake sakamakon da aka samu ya fi gamsarwa. A yanzu an gudanar da gwaje-gwaje na farko akan beraye masu haihuwa wanda, bayan an yi masa magani da kuma bayan makonni huɗu, ƙananan ƙananan beran sun riga sun sami ƙarfin amsawa har zuwa sauti har zuwa decibel 15.
Dukda cewa bincike har yanzu yana da sauran aiki mai tsawo har sai an magance wannan matsalar ta jin a cikin mutane, gaskiyar ita ce, kamar yadda ita kanta masana kimiyya suka nuna, muna fuskantar ci gaban da ba a taba ganin irin sa ba tunda a zahiri sakamakon yana matukar burge duk masu binciken da a yau suke aiki don nemo mafita ga wasu matsalolin likita ta amfani da injiniyan kwayoyin halitta.