Kunyangwe zvichitaridzika kuti vese masayendisiti anotsvaga, neimwe nzira kana imwe, kutungamira mabasa avo kuti vabudirire panodiwa pakurapa gomarara, chokwadi ndechekuti kune zvirwere zvakawanda zvinosuruvarisa kuti zvinokuvadza kunyangwe vakawanda vanhu vakaita seshuga.
In the Lancaster Yunivhesiti (United Kingdom) vane timu izere yevaongorori vanoshanda mukugadzirwa kwemishonga mitsva inokwanisa, chaizvo yekurapa chirwere cheshuga. Sezviri pachena uye sezvakaziviswa, vachiri kushanda mukugadzirwa kwechigadzirwa chitsva kurwisa rudzi rwechipiri chirwere cheshuga, vawana mhinduro iyo yaizoshanda kurapa Alzheimer's.
Mushonga uyu kurapa mhando 2 chirwere cheshuga inogona kushandiswa semushonga weAlzheimer's
Asatikanda mabhero kuti atize'kana chero chinhu chakadai, ndikuudze kuti, sezvo isu tiri kutaura nezve bvunzo dze laboratori, chokwadi ndechekuti parizvino chinhu chega chakawanikwa kugadzira mushonga unokwanisa zvakanyanya kudzoreredza ndangariro kurasikirwa mumakonzoKutanga kuyedza nevanhu, kuchine basa rakawanda rinofanirwa kuitwa, saka kuti chigadzirwa ichi chisvike pamusika, tinogona kutaura zvemakore.
Zvirinani, chokwadi ndechekuti isu tiri nhanho imwe padhuze nekuwana mushonga wechirwere senge Alzheimer's, chimwe chezvirwere zveeurodegenerative izvo, maererano nezvazvino zvidzidzo zvakaitwa nenzira dzakasiyana, zvakawedzera zvakanyanya, kunyanya munyika dzekuMadokero. Chinhu chakakosha ndechekuti, nepo mugore ra2015 pakanga paine mamirioni makumi mana nemasere ezviitiko zvepfungwa pasi rose, nhasi mamirioni 48 emamwe kesi anoonekwa gore rega rega.
Tichifunga izvi, hazvishamise kuti, sekureva kwevakuru vehutano, Alzheimer's yakanyorwa seyakanyanya kukonzera dementia kubvira, nhasi, ine varwere vanopfuura mamirioni makumi matatu, chimiro icho, sekureva kweWHO pachayo, inokura kusvika kumamiriyoni makumi mashanu nematatu emakesi akaonekwa mumakore makumi matatu chete.
Chii chinonzi Alzheimer's uye zvinoitika sei?
Maererano nenyanzvi, zvinoita sekunge Alzheimer's inoitika nekuda kwe kuwanda zvisina kujairika kwe beta amyloid uye tau mapuroteni muuropi hwemunhu. Iko kuunganidzira kunokonzeresa kushomeka kwemitsipa yemaurofibrillary uye chepfu senile plaque, chimwe chinhu icho pakupedzisira chinoguma nekukuvara kwakakomba kune kushanda kwakakodzera kwehuropi.
Kudzokera kuchirongwa chakagadzirwa nevatsvagiri kuLancaster University, zvinoita sekunge rudzi rwechipiri chirwere cheshuga chinhu chakanyanya njodzi yekutambura neAlzheimer's, iri, zvakare, yakabatana zvakanyanya nekuenderera kwechirwere. Izvi zvinodaro nekuti, kutadza kuburitsa kana kushandisa insulin yakabatana zvakananga neyakaipa nzira muuropi hwemurwere iyo inozivikanwa mune ese mamiriro ezvinhu.
Mushonga uyu unokwanisa kudzivirira huropi hwemurwere nenzira dzakasiyana
Sezvakatsanangurwa ne Dr Doug Brown, Director weKutsvagisa nekusimudzira kweAlzheimer's Society:
Pasina kurapwa kutsva mumakore angangoita gumi nemashanu, tinofanirwa kutsvaga nzira nyowani dzekurwisa Alzheimer's. Zvakakosha kuti tiongorore kana mishonga yakagadzirwa kuti irape mamwe mamiriro inogona kubatsira vanhu vane Alzheimer's uye mamwe marudzi ehumwe dementia. Iyi nzira yekutsvaga inogona kuita kuti ikurumidze kuwana anovimbisa mishonga mitsva kune vanhu vanoida.
Kuedza iyi mhando yemhinduro, timu yevaongorori vane basa rekusimudzira chirongwa ichi yakashandisa APP / PS1 mbeva. Rudzi urwu rwemakonzo e-transgenic rudzi rwegonzo rinoratidzira rakachinjika majeni evanhu anokonzera chirwere cheAlzheimer. Pakati pekuedzwa kwakaitwa, zvinofanirwa kucherechedzwa kuti mhuka diki dzakarapwa nemushonga ine chiitiko «katatu agonist»Ndiani aratidza kuti anazvo kugona kuchengetedza huropi munzira dzakasiyana: kuvandudza kudzidza uye kuyeuka kuumbwa, kuchengetedza maseru etsinga, kudzikisa huwandu hweamyloid plaque, kudzikira kusingaperi kwekuzvimba uye kushushikana kweiyo oxidative, uye kunonoka kurasikirwa kwemasero etsinga.
Mamwe Mashoko: Lancaster Yunivhesiti