Ngaphandle kwamathandabuzo, bonke abantu banengxaki enkulu ngayo. intsholongwane yomkhuhlane, isifo esinokubangela ingozi enkulu kuluntu lonke. Ubungqina bento endiyithethayo, umzekelo, eSpain, ilizwe elithe lachaphazeleka kakhulu kwiiveki ezidlulileyo, ngakumbi kwimimandla efana neAragon, La Rioja, Navarra, Catalonia kunye neLizwe laseBasque kwezi veki zidlulileyo, uhlala usenza into epapashiweyo. ingxelo kutshanje yiNational Epidemiological Surveillance Network.
Oku bekunjalo ngenxa yendlela ekhethekileyo yokugonya komkhuhlane eyenziwa minyaka le. Njengeenkcukacha, xelela ukuba, kuba kungenakwenzeka ukulinda ukuba uchaphazeleke ukuba uphuhlise isitofu sokugonya, oko kwenzekayo kukufunda ukuba zeziphi iintlobo ezinokuthi zisichaphazele kwaye ukusuka apho ziphuhlise iyeza lokugonya lonyaka olandelayo. Oku ekugqibeleni kuguqulela kuhlobo lomdlalo wamathuba, ukuba abaphandi banyanisile, isitofu sokugonya sisebenza ngokugqwesileyo, kodwa sinokwenzeka njengalo nyaka apho ukusebenza kwesitofu sehlisiwe ukusuka kuma-40-60% ukuya kuma-25%.
Kutheni le nto isitofu sokugonya siphuhliswa ukusuka kunyaka omnye ukuya kolandelayo kwaye singasoloko sifana?
Nanini na xa abantu bethetha ngolu hlobo lwentsholongwane, inyani kukuba lo mbuzo uvela, kutheni isitofu somkhuhlane esisebenza ngokupheleleyo singaphuhliswanga? Oku, ngaphandle kwamathandabuzo, kuya kuba kokufanelekileyo, ngelishwa intsholongwane yomkhuhlane inokuguqula okuphezulu nto leyo ebangela ukuba intsholongwane itshintshe ngokwaneleyo ukusuka kunyaka omnye ukuya kolandelayo zokuthintela izitofu ezingenako ukuyichaphazela.
Kwelinye icala, into eyinyani kwaye ephawuleka ngayo yonke le nkqubo kukuba, ngaphandle kwenyani yokuba unyaka nonyaka kufuneka sisebenze ukufumana isitofu sokugonya, abaphandi abaninzi banikezela yonke imizamo yabo yokuphuhlisa iyeza elikwaziyo ukunyanga esi sifo ngezifo. Ukungakhathali kweeyure zophando, ngokwephepha elipapashiweyo elivela eJapan, kubonakala ngathi kungaphela emva kokuba iqela labaphandi belizwe likwazile ukuphuhlisa iyeza elinokukunyanga kwesi sifo kwiyure nje ezingama-24.
IJapan ivume kuqala ukusetyenziswa kwesiyobisi esithembisa ukunyanga umkhuhlane kwiiyure nje ezingama-24
Eli chiza litsha lenziwe yinkampani Shionogi ngentsebenziswano ne Switzerland Roche. Naye ngokwakhe ubhaptizwe ngegama lika Ibhokisi yebhokisi yebhaloxavir kwaye ayikho enye into, ubuncinci okwangoku, ngaphandle konyango olusebenzayo olunokusetyenziswa ngokukuko ekunyangeni umkhuhlane wohlobo A kunye nohlobo B. Njengeenkcukacha, sikuxelele ukuba eli chiza, ngokungafaniyo nezinye iindlela zonyango ezikhoyo Intengiso, yipilisi nje enokuthi ilawulwe kube kanye ngomlomo.
Njengoko kuchaziwe UDaniel O'Day, UMlawuli weSebe lezeMithi laseRoche:
I-Baloxavir marboxil yipilisi yokusebenzisa enye xa kuthelekiswa nonyango lweentsuku ezininzi, olunokuthi lubonelele ngezibonelelo ezithile zokucwangcisa ubhubhane. Awunangxaki yokuchasana okunokubonakala ukuba awugqibi unyango.
Ukufezekisa iziphumo ezinjalo, njengoko kuchaziwe, eli chiza livimba iprotein ekufuneka intsholongwane iphindaphinde ngaphakathi kwiiseli ezibamba. Okokugqibela yitsho nje UShionogi sele egqibile ukuvavanywa kweklinikhi yesigaba III ukumisela ukusebenza kweBaloxavir marboxil ngokuthelekisa ukusetyenziswa kwayo kunye ne-placebo kunye nezinye iindlela. Isiphumo sophando sigqiba kwelokuba abaguli abafumene iBaloxavir marboxil bathathe ezimbalwa Iiyure ezingama-24 kwi-avareji yokufumana kwakhona Ngokuchasene neeyure ezingama-42 ezithathiweyo kwizigulana ezinikwe i-placebo. Ezi ziphumo zikhokelele uRhulumente waseJapan ukuba avume kwangaphambili ukusetyenziswa kolu nyango lokulinga.