Tsopano ndizotheka kupulumutsa GIF mu DNA ya mabakiteriya a fecal

fecal bacteria

Masabata angapo apitawa tinali ndi mwayi wolankhula mozama zaukadaulo wina wamakono kwambiri wopangidwa ndi munthu, monga CRISPR-case.9. Mwina dzinalo silikumveka ngati china kwa inu, ngakhale, mwachidule, ndikukuwuzani kuti chifukwa chake titha kupanga mtundu wa 'wodula chibadwa'Izi mkati imatsegula chitseko chachikulu kudziko lodzaza ndi zotheka.

Ngakhale zili choncho ngakhale zitakhala kuti kupita patsogolo kumeneku kukuchitika kopitilira muyeso, monga gulu la asayansi ochokera ku University of Harvard muli nawo sungani fayilo ya GIF ku fecal bacteria DNA, Chowonadi ndichakuti mpaka pano sitikudziwa zabwino zonse zomwe njirayi ingatipatse, kungakhale kopanda phindu, monga kusintha kosalamulirika, zomwe magulu angapo a ofufuza adachenjeza kale.

GIF yosungidwa

Amasankha zomwe zimaonedwa kuti ndi kanema woyamba padziko lapansi kusungidwa mu DNA ya mabakiteriya a fecal

Zingakhale bwanji choncho, ngakhale kuti poyeserera koyambirira timuyo idagwira ndi mitundu ina yazidziwitso, kuwonetsa kupambana kwawo adaganiza zogwiritsa amodzi mwa ma GIF odziwika kwambiri padziko lapansi, yomwe titha kugawa ngati kanema woyamba wopangidwa ndi anthu.

Ndikulankhula za GIF pomwe mutha kuwona kavalo akuyenda. Mtundu wa kanema wopangidwa ndi Kutsogolo Muybridge, kutumidwa, pakulipira ndalama zochuluka panthawiyi, mwa Lelan stanford, kuti asonyeze kuti mphindi yayitali pa mpikisano wamahatchi, imasunga miyendo yonse inayi mlengalenga.

Nthawi zambiri zimachitika ndimatekinoloje ambiri omwe pamapeto pake amadzasintha dziko, zonse zimayamba ndikubetcha pakati pa bilionea Lelan stanford y James keene, panthawiyo Purezidenti wa San Francisco Stock Exchange, komwe a Lelan Stanford adanena kuti panthawi ya mpikisano, kavalo amasunga miyendo yake mlengalenga munthawi inayake pomwe James Keene amakhulupirira zosiyana.

Poganizira izi ndikubweza ndalama zambiri, Eadward Muybridge adapanga zida zomwe zidabatizidwa kutchfuneralhome ntchito yake inali ya tengani zithunzi zambiri motsatira kuti agwire kayendedwe ka kavalo. Zotsatira zake, tili ndi mtundu wa kanema womwe wagwiritsidwa ntchito popanga GIF yoyamba yosungidwa mu DNA kuchokera ku mabakiteriya a fecal.

ADN

Chifukwa chogwiritsa ntchito CRISPR-Cas9, munthuyo tsopano akhoza kusunga zidziwitso m'maketani amoyo a DNA

Kubwerera kuntchito yomwe ofufuza ochokera ku Harvard University adapeza, tapeza kuti adakwanitsa kusunga GIF iyi, monga idasindikizidwira ndi magazini Nature, mu DNA ya mabakiteriya onyansa motero kuwonetsa china chomwe chakhala chikukambidwa kwa nthawi yayitali, kuti DNA ndi hard drive yabwino kwambiri momwe mungasungire zidziwitso zamtundu uliwonse.

Ngakhale pali asayansi ambiri omwe adalankhula za zochititsa chidwi zosungira kuti unyolo wa DNA ungapereke, chowonadi ndichakuti mpaka ukadaulo wa CRISPR-Cas9, zimawoneka kuti tizingodikirira zaka makumi angapo kuti tithe kusunga deta mu tcheni cha DNA. Mosakayikira, chitsanzo chatsopano cha momwe tekinoloje ingasinthire dziko lapansi, makamaka munthawi yomwe anthu ayamba kukhala ndi zovuta zosunga kuchuluka kwa zomwe timatha kupanga.

zinayendera dna

Ndikofunikira kungotsatira ma genome amtundu wa DNA kuti tipeze zomwe tidasunga kale.

Chimodzi mwazinthu zazikulu zomwe gulu lofufuzali lachita ndi mphamvu imagwira ntchito ndi DNA yochokera m'maselo amoyo, m'malo mwa mpaka pano kuti zofananazo zidakwaniritsidwa koma ndi DNA kuchokera kumaselo akufa. Monga tafotokozera mu NatureMankhwala a nyukiliya mwachidziwikire akhala akugwiritsidwa ntchito popanga nambala yokhudzana ndi mapikiselo amtundu uliwonse wazithunzi zomwe zimayenera kupulumutsidwa.

Pofuna kusunga izi, gulu la asayansi limayenera kudziwa kuti ndi njira ziti zomwe zingasungidwe bwino mu genome, lomwe likuyimira kusintha kwatsopano pakugwiritsa ntchito chida ichi. Pomwe amafuna kuti abwezeretse zomwe zasungidwa mu DNA ya mabakiteriya a fecal omwe anali nawo ndondomeko ya genome, ukadaulo womwe umalola kuti DNA iwerengedwe. Pomaliza, tiyenera kudziwa kuti poyesa a 90% njira yolondola.


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